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Abstract #0442

Diagnostic value of intravoxel incoherent motion (IVIM) for differentiating benign and malignant thyroid nodules

hui Tan1, jun CHEN1, YUN-fei ZHA1, liang ZHANG1, jing LU1, Chang-sheng LIU1, and hui LIN2

1Renmin Hospital of Wuhan University, wuhan, China, People's Republic of, 2GE healthcare, shanghai, China, People's Republic of

To preliminary explore the value of intravoxel incoherent motion (IVIM) in the differention between benign and malignant thyroid lesions, 45 patients with 56 thyroid nodules underwent preoperative IVIM (b –1000 s/mm2). Data was postprocessed by IVIM model for quantitation of apparent diffusion coefficient (ADC), perfusion fraction f, diffusivity D and pseudo diffusivity D*. Significant intergroup difference was observed in ADC, D, D*, and f, the f value is the most valuable parameter in identifying the malignant from benign nodules.The IVIM sequence has potential to differentiate the benign from malignant thyroid nodules.

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