Abstract #0500

Fast Quantitative T2 Mapping using Simultaneous-Multi-Slice and Model-Based Reconstruction

Tom Hilbert^1,2,3, Jennifer Schulz⁴, Lauren J. Bains⁴, José P. Marques⁴, Reto Meuli², Jean-Philippe Thiran^2,3, Gunnar Krueger^2,3,5, David G. Norris⁴, and Tobias Kober^1,2,3

¹Advanced Clinical Imaging Technology (HC CMEA SUI DI BM PI), Siemens Healthcare AG, Lausanne, Switzerland, ²Department of Radiology, University Hospital (CHUV), Lausanne, Switzerland, ³LTS5, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, ⁴Radboud University Nijmegen, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Netherlands, ⁵Siemens Medical Solutions USA, Inc., Boston, MA, United States

Long acquisition times of quantitative magnetic resonance imaging (qMRI) are one obstacle that prevents qMRI to be used in clinical routine. Acceleration methods, such as simultaneous-multi-slice and model-based iterative reconstruction proved in the past to allow high acceleration factors in MRI. Here we suggest combining these two methods to allow fast quantitative T2 mapping, yielding a high-resolution (0.7x0.7x3mm³) whole brain (40 slices) acquisition within a clinically acceptable acquisition time of less than 3 minutes. T2 values of the proposed method are similar to the values of the standard method as it is shown on phantom experiments.

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