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Abstract #0533

Quantitative analysis of diagnosing pancreatic fibrosis using Magnetic resonance elastography

Yu Shi1, qiyong guo1, He An1, Kevin J Glaser2, and Ehman L Richard3

1Department of radiology, Shengjing hospital of China medical university, shenyang, China, People's Republic of, 2Rochester, MN, United States, 3Department of radiology, Mayo Clinic, Rochester, MN, United States

An accurate diagnosis of pancreatic fibrosis is important in clinical work. MR elastography (MRE) can be used for staging the degrees of pancreatic fibrosis that reflects the severity of chronic pancreatitis. Our work proved that both fibrosis (P< 0.001) and inflammation (P= 0.014) contribute to higher stiffness of pancreatic parenchyma, excluding fat deposition (P= 0.082). The sensitivity and specificity was 100% and 86% for diagnosing ≥F2, and 100% and 100% for diagnosing =F3 fibrosis stage, respectively.

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