Christian Federau1, Soren Christensen1, Michael Mlynash1, Jenny Tsai1, Sun Kim1, Greg Zaharchuk1, Matus Straka1, Nishant Mishra1, Maarten Lansberg1, and Greg Albers1
We studied the evolution of the infarct volume between
an early post-revascularization scan (within 24 h of symptom onset) and day 5 in
patients of the CRISP and DEFUSE 2 cohort studies. On the early post-revascularization scan, FLAIR
lesions were smaller compared to DWI, but were larger at day 5. The early post-revascularization
stroke volume on DWI, compared to FLAIR, was closer, and correlated better with
the day 5 DWI and FLAIR lesion volumes. Together, our findings suggest that DWI
is a better early surrogate marker of stroke volume.