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Abstract #0602

Stroke Volume Evolution Following Endovascular Therapy on DWI and FLAIR

Christian Federau1, Soren Christensen1, Michael Mlynash1, Jenny Tsai1, Sun Kim1, Greg Zaharchuk1, Matus Straka1, Nishant Mishra1, Maarten Lansberg1, and Greg Albers1

1Stanford University, Stanford, CA, United States

We studied the evolution of the infarct volume between an early post-revascularization scan (within 24 h of symptom onset) and day 5 in patients of the CRISP and DEFUSE 2 cohort studies. On the early post-revascularization scan, FLAIR lesions were smaller compared to DWI, but were larger at day 5. The early post-revascularization stroke volume on DWI, compared to FLAIR, was closer, and correlated better with the day 5 DWI and FLAIR lesion volumes. Together, our findings suggest that DWI is a better early surrogate marker of stroke volume.

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