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Abstract #0721

Pancreatic disease in obesity: observations on fat content, diffusion, T2* relaxometric and mechanical properties in the rat ex vivo

Philippe Garteiser1, Sabrina Doblas1, Jean-Baptiste Cavin1, André Bado1, Vinciane Rebours1,2, Maude Le Gall1, Anne Couvelard1,3, and Bernard E Van Beers1,4

1Center For Research on Inflammation, Inserm U1149, Paris, France, 2Pancreatology Unit, AP-HP, Beaujon Hospital, Clichy, France, 3Pathology department, AP-HP, Bichat Hospital, Paris, France, 4Radiology department, AP-HP, Beaujon Hospital, Clichy, France

Multiparametric assessment of pancreas in the obese rat was used to evaluate alterations linked to obesity-mediated inflammation. Mechanical properties and T2* values are significantly affected by disease, and reflect accurately the histological features of the obese pancreas.

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