Abstract #0721

Pancreatic disease in obesity: observations on fat content, diffusion, T2* relaxometric and mechanical properties in the rat ex vivo

Philippe Garteiser¹, Sabrina Doblas¹, Jean-Baptiste Cavin¹, André Bado¹, Vinciane Rebours^1,2, Maude Le Gall¹, Anne Couvelard^1,3, and Bernard E Van Beers^1,4

¹Center For Research on Inflammation, Inserm U1149, Paris, France, ²Pancreatology Unit, AP-HP, Beaujon Hospital, Clichy, France, ³Pathology department, AP-HP, Bichat Hospital, Paris, France, ⁴Radiology department, AP-HP, Beaujon Hospital, Clichy, France

Multiparametric assessment of pancreas in the obese rat was used to evaluate alterations linked to obesity-mediated inflammation. Mechanical properties and T2* values are significantly affected by disease, and reflect accurately the histological features of the obese pancreas.

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