Abstract #0758

31P-MRI using A Spectrally Selective 3D non-Cartesian FLORET Sequence at 7 T

Prodromos Parasoglou¹, Ryan Brown^1,2, and Guillaume Madelin¹

¹Department of Radiology, New York University School of Medicine, New York, NY, United States, ²NYU WIRELESS, Polytechnic Institute of New York University, Brooklyn, NY, United States

We developed a spectrally selective 3D non-Cartesian FLORET pulse sequence to map phosphorus-containing metabolites in the human tissue. In particular, through this highly efficient pulse sequence we mapped phosphocreatine and γ-adenosine triphosphate at 1.4 cm isotropic nominal voxel size in the human brain. In addition, we were able to map phosphocreatine in the skeletal muscle during exercise and recovery with 6 s temporal resolution. We showed that spectrally selective 3D-FLORET is an efficient pulse sequence that can be used to image ³¹P-containing metabolites in the human tissue when high spatiotemporal resolution is needed.

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