Abstract #0889

MRI assessment of aortic flow in patients with pulmonary hypertension in response to exercise

Jacob Macdonald¹, Omid Forouzan², Naomi Chesler², Christopher Francois³, and Oliver Wieben^1,3

¹Medical Physics, University of Wisconsin - Madison, Madison, WI, United States, ²Biomedical Engineering, University of Wisconsin - Madison, Madison, WI, United States, ³Radiology, University of Wisconsin - Madison, Madison, WI, United States

Cardiopulmonary exercise testing is gaining increased recognition as a useful tool for assessing pulmonary hypertension (PH). Using an MRI-compatible exercise device that allows subjects to exercise in the bore of the magnet, we investigated the effects of exercise stress on blood flow in the ascending aorta in healthy controls and patients with PH. The measurements we obtained demonstrated a decreased exercise capacity in PH subjects and in older controls. Some parameters, such as cardiac output, demonstrated statistically significant changes between rest and stress, while others were unclear due to the relatively low exercise power tolerated by the PH patients.

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