Abstract #0978

Quantitative DCE-MRI as predictors of immediate ablation efficiency in MR-HIFU treatment of uterine fibroids based on reference region model and entire-tumor histogram analysis

Chenxia Li^1,2, Chao Jin¹, Ting Liang^1,2, Gang Niu¹, Yitong Bian¹, Keserci Bilgin³, and Jian Yang^1,2

¹Department of Radiology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi'an, China, People's Republic of, ²Department of Biomedical Engineering, School of Life Science and Technology of Xi’an Jiaotong University, Xi'an, China, People's Republic of, ³Philips Healthcare, Seoul, Korea, Republic of

The aim is to investigate whether quantitative DCE-MRI could be a predictor of immediate ablation efficiency in MR-HIFU of uterine fibroids. 24 eligible female underwent DCE-MRI during screening procedure and immediately after MR-HIFU therapy.They were divided into high non-perfused volume (NPV) ratio (>60%) and low NPV ratio (<60%) group. The reference region model was used for 3D histogram analysis.All histogram metrics of RR-K^trans showed significant difference between two groups. The correlation of RR-K^trans and NPV ratio was significantly negative (r=-0.6). It indicated that the 3D histogram metrics of RR-K^trans might be a sensitive predictor used for patients selection in MR-HIFU.

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