Meeting Banner
Abstract #1004

Comparing Single-Delay, Sequential Multi-delay, and Hadamard Multi-delay ASL for Measuring CBF and Arterial Transit Delay in Normal Subjects and Patients with Cerebrovascular Disease

Samantha Holdsworth1, Audrey Fan1, Marc Lebel2, Zungho Zun3, Ajit Shankaranarayanan4, and Greg Zaharchuk1

1Department of Radiology, Stanford University, Stanford, CA, United States, 2GE Healthcare, Calgary, Canada, 3George Washington University, Washington, DC, United States, 4GE Healthcare, Menlo Park, CA, United States

One promising approach to multi-delay ASL is to perform the labeling using a Hadamard-encoded method, which promises to improve the SNR efficiency compared with sequential multi-delay ASL. In this study, we compared single-delay ASL, sequential multi-delay ASL, and Hadamard-encoded multi-delay ASL in normal subjects and in patients with cerebrovascular disease. Consistent with theory, Hadamard-encoding had better SNR than sequential multi-delay ASL for measuring CBF and arterial transit delay.

This abstract and the presentation materials are available to members only; a login is required.

Join Here