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Abstract #1052

Simultaneous quantification of intragastric secretion and fat distribution

Dian Liu1, Helen Louise Parker2, Jelena Curcic1,2, Sebastian Kozerke1, and Andreas Steingoetter1,2

1Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland, 2Division of Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland

Simultaneous assessment of both intragastric secretion and fat is important in food science but has hitherto been hampered by the bi-exponential relaxation behavior of fat emulsions. In combination with IDEAL, this work introduced a fat correction for rapid T1 mapping, which enabled the simultaneous measurement of the intragastric distribution and temporal development of gastric secretion and fat. Results revealed the interaction between these two components by dilution and mixing, making this method a promising tool to non-invasively assess the emulsification and emptying of ingested fat.

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