Abstract #1055

Diffusion Spectroscopy of White and Brown Adipose Tissues

Sanjay Kumar Verma¹, Kaz Nagashima¹, Swee Shean Lee¹, Tian Xianfeng¹, Jadegoud Yaligar¹, Venkatesh Gopalan¹, Bhanu Prakash KN¹, and S. Sendhil Velan¹

¹Laboratory of Molecular Imaging, Singapore Bioimaging Consortium, Singapore

There are two types of fat tissues, white adipose tissue (WAT) and brown adipose tissue (BAT), which essentially perform opposite functions in whole body energy metabolism. There is a large interest in development of MR Imaging techniques that will be suitable for separating white and brown fat. In this work we have implemented diffusion NMR spectroscopy to differentiate these two types of tissues. Water diffused faster than the fat in both WAT and BAT. Fat diffusion was faster in WAT compared to BAT. Our findings also suggest restricted behavior of fat molecules in BAT and not in WAT.

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