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Abstract #1249

Investigation of the Healthy Nigrosome-1 for the Diagnosis of Parkinson’s Disease using Multiple Susceptibility based MRI Techniques

Kyung Mi Lee1 and Hyug-Gi Kim2

1Radiology, Kyung Hee University Hospital, Seoul, Korea, Republic of, 2Biomedical Engineering, College of Electronic Information Engineering, Kyung Hee University, Gyeonggi-do, Korea, Republic of

Nigrosome-1 region that is affected to the loss of dopaminergic neurons is one of the important characteristics of Parkinson’s disease (PD). To evaluate the early stage of PD and investigate the main mechanisms of nigrosome degeneration using MR images, the susceptibility based MRI techniques were performed: R2* (=1/T2*) map, SWI and QSM map in seven elderly healthy subjects that are reference subjects for PD.

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