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Abstract #1278

A Quantitative Evaluation of Normal Appearing White Matter in Multiple Sclerosis: ViSTa MWI and SE MWI.

Joon Yul Choi1, In Hye Jeong2, Se-Hong Oh3, Chang-Hyun Oh4,5, Ho Jin Kim2, and Jongho Lee1

1Laboratory for Imaging Science and Technology, Department of Electrical and Computer Engineering, Seoul National University, Seoul, Korea, Republic of, 2Department of Neurology, Research Institute and Hospital of National Cancer Center, Goyang, Korea, Republic of, 3Imaging Institute, Cleveland Clinic Foundation, Cleveland, OH, United States, 4Department of Electronics and Information Engineering, Korea University, Seoul, Korea, Republic of, 5ICT Convergence Technology Team for Health&Safety, Korea University, Seoul, Korea, Republic of

This study investigated the applicability of ViSTa-MWI for the detection of myelin damage in MS. The results show ViSTa-MWI sensitively detects normal appearing white matter damage with better reliability than SE-MWI. Additionally, ViSTa-MWI can discriminate T1 isointense lesions from T1 hypointense lesions.

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