Abstract #1278

A Quantitative Evaluation of Normal Appearing White Matter in Multiple Sclerosis: ViSTa MWI and SE MWI.

Joon Yul Choi¹, In Hye Jeong², Se-Hong Oh³, Chang-Hyun Oh^4,5, Ho Jin Kim², and Jongho Lee¹

¹Laboratory for Imaging Science and Technology, Department of Electrical and Computer Engineering, Seoul National University, Seoul, Korea, Republic of, ²Department of Neurology, Research Institute and Hospital of National Cancer Center, Goyang, Korea, Republic of, ³Imaging Institute, Cleveland Clinic Foundation, Cleveland, OH, United States, ⁴Department of Electronics and Information Engineering, Korea University, Seoul, Korea, Republic of, ⁵ICT Convergence Technology Team for Health&Safety, Korea University, Seoul, Korea, Republic of

This study investigated the applicability of ViSTa-MWI for the detection of myelin damage in MS. The results show ViSTa-MWI sensitively detects normal appearing white matter damage with better reliability than SE-MWI. Additionally, ViSTa-MWI can discriminate T₁ isointense lesions from T₁ hypointense lesions.

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