Abstract #1291

Lobule-wise quantitative T1 and T2* analysis of cerebellar grey matter in multiple sclerosis patients at 7T MRI

Yohan Boillat¹, Kieran O'Brien^2,3, Mário João Fartaria de Oliveira^4,5, Guillaume Bonnier^1,5,6, Gunnar Krueger^5,7, Wietske van der Zwaag^1,8, and Cristina Granziera^1,5,6,9

¹Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, ²Siemens Healthcare Pty Ltd., Brisbane, Australia, ³University of Queensland, St-Lucia, Australia, ⁴University of Lausanne, Lausanne, Switzerland, ⁵Advanced Clinical Imaging Technology Group, Siemens, Lausanne, Switzerland, ⁶Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland, ⁷Healthcare Sector IM&WS S, Siemens Schweiz AG, Lausanne, Switzerland, ⁸Spinoza Centre for Neuroimaging, Amsterdam, Switzerland, ⁹Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, United States

We compared ultra-high field, high resolution quantitative T₁ and T₂* measurements in the cerebellum of MS patients to that of healthy controls. A correlation between the multiple sclerosis functional scale scores and local T₂* values was found for several motor and cognitive related lobules. No significant differences between groups were found.

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