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Abstract #1291

Lobule-wise quantitative T1 and T2* analysis of cerebellar grey matter in multiple sclerosis patients at 7T MRI

Yohan Boillat1, Kieran O'Brien2,3, Mário João Fartaria de Oliveira4,5, Guillaume Bonnier1,5,6, Gunnar Krueger5,7, Wietske van der Zwaag1,8, and Cristina Granziera1,5,6,9

1Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 2Siemens Healthcare Pty Ltd., Brisbane, Australia, 3University of Queensland, St-Lucia, Australia, 4University of Lausanne, Lausanne, Switzerland, 5Advanced Clinical Imaging Technology Group, Siemens, Lausanne, Switzerland, 6Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland, 7Healthcare Sector IM&WS S, Siemens Schweiz AG, Lausanne, Switzerland, 8Spinoza Centre for Neuroimaging, Amsterdam, Switzerland, 9Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, United States

We compared ultra-high field, high resolution quantitative T1 and T2* measurements in the cerebellum of MS patients to that of healthy controls. A correlation between the multiple sclerosis functional scale scores and local T2* values was found for several motor and cognitive related lobules. No significant differences between groups were found.

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