Meeting Banner
Abstract #1293

T1ρ MRI Demonstrates Increased Contrast-to-Noise-Ratio in MS Lesions Compared to T2

Jay V Gonyea1, Richard Watts1, Angela Applebee2, Trevor Andrews1,3, Scott Hipko1, Joshua P Nickerson1, Lindsay Thornton4, and Christopher G Filippi5

1Radiology-MRI Center for Biomedical Imaging, University of Vermont College of Medicine, Burlington, VT, United States, 2Neurological Sciences, University of Vermont College of Medicine, Burlington, VT, United States, 3Philips Health Tech, Cleveland, OH, United States, 4Radiology, University of Florida, Gainesville, FL, United States, 5Radiology, North Shore University Hospital-Long Island Jewish, New York, NY, United States

Quantitative MRI measures such as T2 are limited in their ability of staging MS progression. Tmay be sensitive to low-frequency chemical exchange between proteins and extracellular water. A 3D TSE with whole-brain coverage, spin-lock times of 0, 20, 40, 60, 80, and 100 ms spin-lock times was acquired at 500 Hz. We found that T provides better contrast-to-noise-ratio (CNR) than T2.

This abstract and the presentation materials are available to members only; a login is required.

Join Here