Abstract #1388

Estimating damage to the blood-brain barrier from radiotherapy treatment

Magne Kleppestø¹, Christopher Larsson¹, and Atle Bjornerud^1,2

¹The Intervention Centre, Oslo University Hospital, Oslo, Norway, ²Department of Physics, University of Oslo, Oslo, Norway

Brain tumors are usually subjected to radiation therapy upon diagnosis. In this work, it is made an attempt at investigating if this therapy might cause injury to the non-cancerous parts of the brain. To this end dynamic contrast-enhanced MRI was used to estimate leakage across the blood-brain barrier.22 patients were imaged before and after undergoing a treatment schedule, and findings from the two examinations were compared to uncover any change. The data shows no significant variation in either permeability or blood plasma volume.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.