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Abstract #1389

MR appearance of Primary central nervous system lymphoma: as prognostic factors influencing the response to clinical treatment

jing Liu1 and shuixing Zhang1

1Radiology, Department of Radiology, Guangdong Academy of Medical Sciences/Guangdong General Hospital, Guangzhou, Guangzhou, China, People's Republic of

Currently, the treatment response in primary central nervous system lymphoma (PCNSL) is monitored by serial contrast-enhanced anatomic MR imaging, which often showing characteristic radio-morphological features such as lesion location, strong and homogenous contrast-enhancement, moderate edema and absence of necrosis. The purpose of our study was to investigate the objective response rate (ORR) and identify MR findings as predictors to evaluate the therapeutic response in PCNSL. Our result shows that tumor size, number, location, homogenous enhancement and the planned therapeutic strategy were independent factors correlated with treatment response in patients of PCNSL.

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