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Abstract #1437

Intracranial aneurysm wall permeability: a potential risk predictor for rupture

Qi Haikun1, Peng Liu2, and Huijun Chen1

1Center for Biomedical Imaging Research, School of Medicine, Tsinghua University, Beijing, China, People's Republic of, 2Department of Neurosurgical, Beijing Neurosurgical Institute and Beijing Tiantan Hospital, Beijing, China, People's Republic of

The rupture risk prediction of unruptured intracranial aneurysm (IA) is very important in clinical practice and increased knowledge of predictors for IA rupture is needed. IA wall permeability has great potential for aneurysm rupture risk prediction, and can be quantified by DCE-MRI. In this study, we measured IA wall permeability using DCE-MRI, and compared it with established clinical/imaging risk metrics. We found IA wall permeability may be independent of aneurysm size and IA wall enhancement providing distinctive information for IA rupture risk prediction.

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