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Abstract #1480

Temporal resolution improvement of calibration-free dynamic contrast-enhanced MRI with compressed sensing optimized turbo spin echo: The effects of replacing turbo factor with compressed sensing accelerations

SoHyun Han1 and HyungJoon Cho1

1Biomedical Engineering, Ulsan National Institute Science and Technology, Ulsan, Korea, Republic of

In vivo estimation of Gd-concentration in dynamic contrast enhanced (DCE)-MRI are often compromised from non-negligible T2* effect and limited temporal resolution. In this study, we introduce compressed sensing assisted turbo spin echo (CS-TSE) acquisition to provide accurate Gd-concentration estimation without the need of additional signal calibration, and to achieve a sub-second temporal resolution with extended slice coverage. Phantom verification followed by in vivo arterial input function (AIF) studies validated the faithful concentration estimation of CS-TSE. Robust measurement of first-pass kidney feeding AIF with increased temporal resolution was demonstrated with sub-second temporal resolution.

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