In
vivo estimation
of Gd-concentration in dynamic contrast enhanced (DCE)-MRI are often
compromised from non-negligible T2* effect
and limited temporal resolution. In this study, we introduce
compressed sensing assisted turbo spin echo (CS-TSE) acquisition to provide accurate
Gd-concentration estimation without the need of additional signal calibration,
and to achieve a sub-second temporal resolution with extended slice coverage. Phantom
verification followed by in vivo arterial
input function (AIF) studies validated the faithful concentration estimation
of CS-TSE. Robust measurement of first-pass kidney feeding AIF with increased
temporal resolution was demonstrated with sub-second temporal resolution.
