Abstract #1480

Temporal resolution improvement of calibration-free dynamic contrast-enhanced MRI with compressed sensing optimized turbo spin echo: The effects of replacing turbo factor with compressed sensing accelerations

SoHyun Han¹ and HyungJoon Cho¹

¹Biomedical Engineering, Ulsan National Institute Science and Technology, Ulsan, Korea, Republic of

In vivo estimation of Gd-concentration in dynamic contrast enhanced (DCE)-MRI are often compromised from non-negligible T2* effect and limited temporal resolution. In this study, we introduce compressed sensing assisted turbo spin echo (CS-TSE) acquisition to provide accurate Gd-concentration estimation without the need of additional signal calibration, and to achieve a sub-second temporal resolution with extended slice coverage. Phantom verification followed by in vivo arterial input function (AIF) studies validated the faithful concentration estimation of CS-TSE. Robust measurement of first-pass kidney feeding AIF with increased temporal resolution was demonstrated with sub-second temporal resolution.

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