Abstract #1481

Gradient optimization using active contour for rapid breast DCE-MRI

Pavan poojar¹, Bikkemane Jayadev Nutandev², Nithin N Vajuvalli¹, C.K. Dharmendra Kuman², Ramesh Venkatesan³, and Sairam Geethanath¹

¹Medical Imaging Research Centre, Dayananda Sagar College of Engineering, Bangalore, India, ²Bangalore, India, ³Wipro-GE Healthcare, Bangalore, India

In dynamic scans, the significant values of k-space dependent on the shape of the organ which leads to arbitrary k-space trajectories. Gradient optimization for arbitrary k-space trajectory using active contour is a new acquisition technique that has been applied on six DCE breast data. The arbitrary k-space trajectory was obtained by active contour and gradients are optimized by employing convex optimization based on hardware constraints. Image reconstruction was performed using Fourier transform with density compensation. $$$K^{trans}$$$ and Ve maps were generated for different acceleration factors (1x, 2x, 3x, 4x and 10x) on tumor region to demonstrate utility of the method.

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