Abstract #1485

Reproducibility of abdominal perfusion imaging using velocity selective arterial spin labeling

Marijn van Stralen¹, Esben Thade Petersen^1,2, Jeroen Hendrikse¹, and Clemens Bos¹

¹University Medical Center Utrecht, Utrecht, Netherlands, ²Danish Research Center for MR, Hvidovre, Denmark

Abdominal perfusion imaging using contrast media injection is potentially nephrotoxic. Arterial spin labeling (ASL), employing endogenous contrast, was shown using spatially selective labeling strategies. We investigated the reproducibility of velocity selective ASL (VS-ASL), which eliminates delicate label planning and possibly improves perfusion SNR by labeling closer to the target tissue. We show that abdominal VS-ASL is feasible in healthy volunteers and overcome labeling artifacts by pacing and triggering the acquisition with good temporal SNR. However, VS-ASL is sensitive to motion during readout, deteriorating reproducibility. It could benefit from outlier rejection techniques and retrospective motion correction.

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