A simple and reliable perfusion phantom to measure precise and repeatable arterial spin labeled quantitative perfusion
Joshua S. Greer1,2, Keith Hulsey2, Robert E. Lenkinski2,3, and Ananth J. Madhuranthakam2,3
1Bioengineering, University of Texas at Dallas, Richardson, TX, United States, 2Radiology, UT Southwestern Medical Center, Dallas, TX, United States, 3Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States
Arterial spin labeling (ASL) is a rapidly growing area of
interest, primarily because of its ability to provide quantitative perfusion
maps non-invasively. But, for the technique to be adopted for clinical use,
these quantitative measurements need to be accurate and robust, which will
require a quality controlled perfusion phantom to ensure consistency for
different magnet strengths and manufacturers. In this study, we demonstrate a
simple perfusion flow phantom that can be used to test the precision and
repeatability of ASL perfusion measurements.
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