Meeting Banner
Abstract #1509

Monitoring therapeutic response on medullary thyroid carcinoma in chemotherapy by amide proton transfer (APT) imaging in an orthotopic mouse model

Keisuke Ishimatsu1, Karine Pozo2, Shanrong Zhang1, Koji Sagiyama1, Osamu Togao1, James Bibb3, and Masaya Takahashi1

1Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, United States, 2Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, United States, 3Department of Psychiatry / Harold C. Simmons Comprehensive Cancer Center / Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX, United States

The objective is to investigate whether amide proton transfer (APT) imaging is useful for evaluation of anticancer treatment responses in chemotherapy. We compared the temporal changes of APT signal with the different treatment strategies using two new drugs, administered individually or in combination, in a mouse model of medullary thyroid carcinoma.

This abstract and the presentation materials are available to members only; a login is required.

Join Here