Lei Jiang1, Paul Territo1, Brian McCarthy1, Amanda A. Riley1, Sourajit Mustafi1, Yu-Chien Wu1, Bruce Molitoris2, Gary Hutchins1, and Chen Lin1
1Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, United States, 2Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, United States
The objective of this study is to evaluate the capability of
quantitative MRI techniques to measure physiological changes associated with changes
in renal function in a rat model. Our investigation suggest that the results of
T2* mapping, intra-voxel incoherent motion (IVIM), and T1ρ imaging are
comparable to the published results. These techniques can be used to assess and
monitor different aspects of physiological changes in kidney fibrosis.