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Abstract #1946

In vivo multifrequency MR elastography of the human prostate using a surface-based compressed air driver operated in the lower frequency regime

Florian Dittmann1, Heiko Tzschätzsch1, Jing Guo1, Sebastian Hirsch1, Jürgen Braun2, and Ingolf Sack1

1Institute of Radiology, Charité, Berlin, Germany, 2Department of Medical Informatics, Charité, Berlin, Germany

We demonstrate the feasibility of in vivo prostate exam utilizing shear waves induced by pressurized-air actuators previously developed for abdominal MRE. High wave amplitudes throughout the prostate were achieved in the lower frequency regime from 30 to 50 Hz. Using a 2D multifrequency wave number inversion algorithm, wave speed maps with sufficiently high resolution are obtained to discriminate between the central zone and peripheral zone despite longer wavelengths pertaining to lower vibration frequencies. The proposed MRE setup promises robust and easy-to-use applications in the clinic without the need of specialized hardware in addition to the abdominal MRE setup.

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