Abstract #1948

Quantification of Breast Stiffness using Magnetic Resonance Elastography at 3T: A Reproducibility Study

Prateek Kalra¹, Arunark Kolipaka, PhD¹, Jeffrey R. Hawley, MD¹, and Brian Raterman¹

¹Radiology, Ohio State University Wexner Medical Center, Columbus, OH, United States

Magnetic resonance elastography (MRE) is a non-invasive technique to estimate stiffness of soft tissues and has been applied in the breast. However, none of the earlier studies have extensively tested MRE to induce vibrations in the breast using a soft sternum driver at higher field strength and its repeatability of stiffness measurements. The aim of the study is to estimate breast stiffness using MRE by inducing vibrations using a soft sternum driver in normal volunteers at 3T and to determine the reproducibility of stiffness measurements. Preliminary results show that the MRE-derived stiffness values are reproducible in normal volunteers at 3T and can be further extended to detect breast tumors in patients.

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