Meeting Banner
Abstract #2013

White matter alterations in young adults born extremely preterm: a microstructural point of view.

Zach Eaton-Rosen1, Andrew Melbourne1, Joanne Beckmann2, Eliza Orasanu1, Nicola Stevens3, David Atkinson4, Neil Marlow2, and Sebastien Ourselin1

1TIG, UCL, London, United Kingdom, 2UCL EGA Institute for Women's Health, London, United Kingdom, 3UCLH, London, United Kingdom, 4CMIC, UCL, London, United Kingdom

We used NODDI and DTI in order to investigate the differences in white matter between young adults born at term, and those born at fewer than 26 weeks completed gestation, using TBSS. The differences in FA were closely mirrored by the differences in orientation dispersion index (ODI) while the intra-axonal volume fraction (Vi) did not show significant differences in the same regions. This suggests that the ODI may be more sensitive to indicators of being born preterm than Vi in the white matter.

This abstract and the presentation materials are available to members only; a login is required.

Join Here