Eva Heckova1, Stephan Gruber1, Bernhard Strasser1, Michal Povazan1, Gilbert Hangel1, Siegfried Trattnig1,2, and Wolfgang Bogner1
1High Field MR Center, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, 2Christian Doppler Laboratory for Clinical Molecular MR Imaging, Vienna, Austria
resonance spectroscopic imaging (MRSI) allows to measure different
metabolites in the brain. SNR and spectral resolution increases at
higher magnetic fields. We compared FID-MRSI with ultra short
acquisition delay (1.5 ms) and a very high spatial resolution in the
same group of healthy subjects at 3T and 7T. We found 1.87-fold
increased SNR and decreased CRLBs at 7T in comparison with 3T. The
higher spectral resolution at 7T allows to distinguish between NAA
and NAAG and reliable detect other metabolites like Glx or Tau.
Accelerating the acquisition techniques leads to lower SNR, however
not to substantially decreased quantification precision.