Abstract #2358

Comparison of high-resolution FID-MRSI in the brain between 3 and 7 Tesla

Eva Heckova¹, Stephan Gruber¹, Bernhard Strasser¹, Michal Povazan¹, Gilbert Hangel¹, Siegfried Trattnig^1,2, and Wolfgang Bogner¹

¹High Field MR Center, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, ²Christian Doppler Laboratory for Clinical Molecular MR Imaging, Vienna, Austria

Magnetic resonance spectroscopic imaging (MRSI) allows to measure different metabolites in the brain. SNR and spectral resolution increases at higher magnetic fields. We compared FID-MRSI with ultra short acquisition delay (1.5 ms) and a very high spatial resolution in the same group of healthy subjects at 3T and 7T. We found 1.87-fold increased SNR and decreased CRLBs at 7T in comparison with 3T. The higher spectral resolution at 7T allows to distinguish between NAA and NAAG and reliable detect other metabolites like Glx or Tau. Accelerating the acquisition techniques leads to lower SNR, however not to substantially decreased quantification precision.

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