Grzegorz L. Chadzynski1,2, Jonas Bause2, G. Shajan2, Rolf Pohmann2, Klaus Scheffler1,2, and Philipp Ehses1,2
1Biomedical Magnetic Resonance, Eberhard-Karls University of Tübingen, Tübingen, Germany, 2High-field Magnetic Resonance Center, Max Planck Institute for Biological Cybernetics, Tübingen, Germany
The aim was to design a MRSI-FID
sequence for ultra-high field applications with high acquisition speed and
sampling efficiency. The sequence allows acquisition of a 32×32 voxel matrix
within approximately 2 min, down to 30 sec using parallel imaging. We have
examined the suitability of this approach for assessing biochemical changes in
the human visual cortex during a visual stimulus. Obtained results were in
accordance with other functional MRS studies and indicate that the developed
sequence is suitable for rapid monitoring of stimulus evoked changes in human
brain biochemistry at a very high spatial resolution.
