Abstract #2374

1H-MRS of Human Liver at 3 T: Relaxation Times and Metabolite Concentrations

Jan Weis¹, Fredrik Rosqvist², Joel Kullberg¹, Ulf Risérius², and Håkan Ahlström¹

¹Department of Radiology, Uppsala University, Uppsala, Sweden, ²Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden

Proton MR spectroscopy of healthy human liver was performed at 3 T MR scanner. The purpose of this study was to estimate glycogen (Glycg), choline-containing compounds (CCC), water, and lipid (-CH₂-)_n relaxation times T₁, T₂, and absolute concentration of Glycg, CCC, and fat. Experiments were performed using multiple breath-hold technique. Spectra were processed by LCModel. T₁ and T₂ values were obtained by mono-exponential fitting spectral intensities versus repetition or echo times. Quantification of liver Glycg, CCC and lipids is important for understanding changes in lipid and glucose metabolism due to metabolic disorders.

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