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Abstract #2374

1H-MRS of Human Liver at 3 T: Relaxation Times and Metabolite Concentrations

Jan Weis1, Fredrik Rosqvist2, Joel Kullberg1, Ulf Risérius2, and Håkan Ahlström1

1Department of Radiology, Uppsala University, Uppsala, Sweden, 2Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden

Proton MR spectroscopy of healthy human liver was performed at 3 T MR scanner. The purpose of this study was to estimate glycogen (Glycg), choline-containing compounds (CCC), water, and lipid (-CH2-)n relaxation times T1, T2, and absolute concentration of Glycg, CCC, and fat. Experiments were performed using multiple breath-hold technique. Spectra were processed by LCModel. T1 and T2 values were obtained by mono-exponential fitting spectral intensities versus repetition or echo times. Quantification of liver Glycg, CCC and lipids is important for understanding changes in lipid and glucose metabolism due to metabolic disorders.

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