Benjamin C Rowland1, Fatah Adan1, Huijun Liao1, and Alexander P Lin1
B0 frequency drift is a well-known phenomenon which can have a significant impact on MR spectroscopy, affecting both peak resolution and metabolite quantification. B0 drift is particularly associated with gradient-heavy EPI sequences like DTI. In a study of 53 subjects receiving DTI and MRS, the mean FWHM more than doubled as a result of frequency drift and metabolite concentrations were often
misestimated by LC Model.