Abstract #2375

Gradient-heavy sequences degrade the quality of subsequent spectroscopy acquisitions

Benjamin C Rowland¹, Fatah Adan¹, Huijun Liao¹, and Alexander P Lin¹

¹Centre for Clinical Spectroscopy, Brigham and Women's Hospital, Boston, MA, United States

B0 frequency drift is a well-known phenomenon which can have a significant impact on MR spectroscopy, affecting both peak resolution and metabolite quantification. B0 drift is particularly associated with gradient-heavy EPI sequences like DTI. In a study of 53 subjects receiving DTI and MRS, the mean FWHM more than doubled as a result of frequency drift and metabolite concentrations were often misestimated by LC Model.

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