Abstract #2376

Elucidation of the downfield spectrum of human brain at 7T using multiple inversion recovery delays and echo times

Nicole D Fichtner^1,2, Anke Henning^2,3, Niklaus Zoelch², Chris Boesch¹, and Roland Kreis¹

¹Depts. Radiology and Clinical Research, University of Bern, Bern, Switzerland, ²Institute for Biomedical Engineering, UZH and ETH Zurich, Zurich, Switzerland, ³Max Planck Institute for Biological Cybernetics, Tuebingen, Germany

Characterization of the full ¹H spectrum may allow for better monitoring of pathologies and metabolism in humans. The downfield part (5-10ppm) is currently less well characterized than upfield; this work aims to benefit from higher field strength in order to quantify T₁ and T₂ in the downfield spectrum in human grey matter at 7T. We fitted downfield spectra to a heuristic model and obtained relaxation times for twelve peaks of interest. The T₁’s are higher than those at 3T downfield; peaks with lower T₁’s may include macromolecules. The T₂’s are mostly shorter than those reported for upfield peaks at 7T.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.