Abstract #2533

MRI relaxation parameters predict functional outcome after experimental myocardial infarction

Sebastian Haberkorn¹, Christoph Jacoby¹, and Ulrich Flögel¹

¹Molecular Cardiology, Heinrich Heine University, Düsseldorf, Germany

In the present study, we systematically compared myocardial tissue characterization by Gd-based techniques with intrinsic T1/T2 mapping and their correlation with local cardiac function after experimental myocardial infarction (MI). We found that pre-contrast T1 mapping with variable flip angle analysis carried out 1 day after MI predicts the functional outcome after 21 days at least as reliable as LGE. Compared to the latter technique providing plain signal enhancement, the current approach determines quantitative maps with a large dynamic range, which may pave the way for reliable myocardial tissue characterization without any CA.

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