Abstract #2680

Evaluate Relative Helicity of Aortic Flow for Marfan Syndrome by 4D Flow Phase Contrast MRI

Pin-Chen Chen¹, Hsin-Hui Chiu², Wen-Yih Isaac Tseng³, and Hsu-Hsia Peng⁴

¹Institute of Systems Neuroscience, Hsinchu, Taiwan, ²Department of Pediatrics, Taipei, Taiwan, ³Center for Optoelectronic Biomedicine, Taipei, Taiwan, ⁴Department of Biomedical Engineering and Environmental Sciences, Hsinchu, Taiwan

We aim to evaluate relative helicity of aortic flow for patients with Marfan syndrome (MFS) by 4D flow phase-contrast MRI. An individual helicity_AED mapping was composed to provide the information of the spatiotemporal distribution of relative helicity. The E sign represents the relative helicity cores shown in the early diastole whereas D sign represents the relative helicity core shown time-delayed and downstream. The A sign represents an additional relative helicity core other than D, E, or the normal single cores. MFS patients showed abnormal relative helicity core in helicity_AED mapping, which provided promising approaches for patient managements in the future.

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