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Abstract #2730

Analyzing the Texture of Suspicious Lesions in the Female Breast with ADC-mapping in DWIBS and DWI

Jana Tesdorff1, Frederik Laun2, Stefan Delorme1, Wolfgang Lederer3, Heidi Daniel4, Heinz-Peter Schlemmer1, and Sebastian Bickelhaupt1

1Radiology, German Cancer Research Center, Heidelberg, Germany, 2Medical Physics, German Cancer Research Center, Heidelberg, Germany, 3Heidelberg, Germany, 4Mannheim, Germany

Diffusion-weighted imaging (DWI) can be helpful to differentiate benign and malignant lesions in the female breast. We compared the diagnostic performance of conventional DWI and DWIBS (DWI with background suppression) derived ADC maps with different definitions of the region of interest used to measure the ADC value (1.5T Philips). Texture analysis of suspicious breast lesions was performed utilizing ADC mapping in 59 lesions. Statistical analysis revealed the highest accuracy for lesion differentiation if using the mean ADC-value calculated of three small regions-of interest in the DWIBS derived ADC.

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