Abstract #2731

Histogram-metrical DCE-MRI based Quantitative Discrimination of Breast Masses

Chao Jin¹, Ting Liang¹, Hongwen Du¹, Gang Niu¹, Zihua Su¹, Peng Cao¹, Yonghao Du¹, Chenxia Li¹, Yitong Bian¹, and Jian Yang¹

¹Department of Radiology, the First Affiliated Hospital of Xi’an Jiaotong University, Xi'an, China, People's Republic of

To clarify the diagnostic efficiency of histogram and mean in tumor detection, this study aims to compare the efficiency of mean and histogram metrics (i.e. skewness, kurtosis, median, variance, entropy and energy) of K^trans and k_ep at transverse slice with tumor biggest diameter in discriminating benign lesion, grade II- and III-invasive ductal carcinomas (IDC). The results indicate that in breast DCE-MRI, both mean and histogram-metrics provide roughly comparable values in identifying malignancy from benignancy. However, histogram-metrics are considerably more informative and enable to discriminate pathological grade of IDCs. k_eppresented better diagnostic efficiency than K^trans.

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