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Abstract #2731

Histogram-metrical DCE-MRI based Quantitative Discrimination of Breast Masses

Chao Jin1, Ting Liang1, Hongwen Du1, Gang Niu1, Zihua Su1, Peng Cao1, Yonghao Du1, Chenxia Li1, Yitong Bian1, and Jian Yang1

1Department of Radiology, the First Affiliated Hospital of Xi’an Jiaotong University, Xi'an, China, People's Republic of

To clarify the diagnostic efficiency of histogram and mean in tumor detection, this study aims to compare the efficiency of mean and histogram metrics (i.e. skewness, kurtosis, median, variance, entropy and energy) of Ktrans and kep at transverse slice with tumor biggest diameter in discriminating benign lesion, grade II- and III-invasive ductal carcinomas (IDC). The results indicate that in breast DCE-MRI, both mean and histogram-metrics provide roughly comparable values in identifying malignancy from benignancy. However, histogram-metrics are considerably more informative and enable to discriminate pathological grade of IDCs. kep presented better diagnostic efficiency than Ktrans.

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