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Abstract #2733

Removing Silicone Artifacts in Diffusion-Weighted Breast MRI by Means of Shift-Resolved Spatiotemporally Encoding

Eddy Solomon1, Noam Nissan2, Rita Schmidt1, Edna Furman-Haran3, Uriel Ben-Aharon4, and Lucio Frydman1

1Chemical Physics Department, Weizmann Institute of Science, Rehovot, Israel, 2Biological Regulation Department, Weizmann Institute of Science, Rehovot, Israel, 3Unit of Biological Services, Weizmann Institute of Science, Rehovot, Israel, 4Breast Surgery Unit, Meuhedet Clinic, Ashdod, Israel

A new ADC-mapping methodology based on SPatio-temporal ENcoding (SPEN) was applied to augmented breasts, organs possessing multiple spectral components. SPEN provides a robust single-shot alternative to echo-planar-imaging (EPI) in terms of overcoming B0-inhomogeneities, while being able to resolve—and thereby suppress—the contributions of different chemical sites. Diffusion SPEN measurements were carried out at 3T on healthy volunteers with silicone-implant augmentation and compared against SE-EPI counterparts, confirming SPEN’s ability to yield more reliable ADC maps, free from the dominant silicone signal contributions, in a single shot. This opens new screening possibilities for cancer detection in breast augmented patients.

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