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Abstract #2817

Fast 3D Acquisition for Quantitative Mapping and Synthetic Contrasts Using MIRACLE and trueCISS

Tom Hilbert1,2,3, Damien Nguyen4,5, Jean-Philippe Thiran2,3, Gunnar Krueger2,3,6, Oliver Bieri4,5, and Tobias Kober1,2,3

1Advanced Clinical Imaging Technology (HC CMEA SUI DI BM PI), Siemens Healthcare AG, Lausanne, Switzerland, 2Department of Radiology, University Hospital (CHUV), Lausanne, Switzerland, 3LTS5, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 4Radiological Physics, Department of Radiology, University of Basel Hospital, Basel, Switzerland, 5Department of Biomedical Engineering, University of Basel, Basel, Switzerland, 6Siemens Medical Solutions USA, Inc., Boston, MA, United States

Quantitative imaging promises to be a good biomarker of disease but requires long acquisition times, especially when 3D acquisition techniques are used. Here we propose to use a highly undersampled 3D phase-cycled balanced steady-state free-precession sequence in combination with the reconstruction methods MIRACLE and trueCISS, providing quantitative maps (T2,T1,M0). Additionally, synthetic contrasts can be generated using the previously calculated quantitative maps and signal models, exemplarily shown for bSSFP, T2- and T1-weighted contrast. In summary, the proposed method provides a set of quantitative maps and various conventional contrasts using a single 3:31min acquisition.

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