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Abstract #2847

High-Resolution Quantitative Susceptibility Mapping of Free-Breathing Human Lung

Hongjiang Wei1, Luke Xie2, Yuyao Zhang1, and Chunlei Liu1,3

1Brain Imaging and Analysis Center, Duke University, Durham, NC, United States, 2Utah Center for Advanced Imaging Research, Department of Radiology, University of Utah, Salt Lake City, UT, United States, 3Department of Radiology, School of Medicine, Duke University, Durham, NC, United States

In the pulmonary tissue, strong-susceptibility-induced field perturbation is mostly a source of artifact resulting in severe distortion. Breathing artifacts pose further challenges, especially in pediatric populations. These artifacts coupled with the intrinsic low proton SNR make it extremely difficult to perform quantitative susceptibility mapping in the lung. State-of-the-art STAR-QSM method combined with the recently developed locally low rank parallel imaging method could further reduce motion artifacts and allow free-breathing high resolution QSM of the lung.

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