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Abstract #2860

Investigating the magnetic susceptibility of skeletal muscle at 7 T

Benjamin Tendler1 and Richard Bowtell1

1Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, United Kingdom

There has been longstanding interest in the anisotropic magnetic properties of muscle tissue, but to date there has been little examination of these properties using MRI. Here we describe an initial examination of muscle via field mapping measurements carried out at 7T on phantoms containing small pieces of muscle embedded in agar. The results indicate that the susceptibility of this muscle is diamagnetic (~-100ppb) with respect to agar and only weakly anisotropic (<5 ppb). There was a significant uniform and orientation-independent positive frequency offset inside the muscle of 30 ppb most likely due to chemical exchange effects.

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