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Abstract #2867

Saturation Recovery Fast Spin Echo Method for Rapid T1 Mapping of Mouse Kidney

Kai Jiang1, Hui Tang1, Prassana K. Mishra2, Slobodan I. Macura2, and Lilach O. Lerman1

1Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, United States, 2Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, United States

In this study, a saturation recovery fast spin echo method was developed for fast T1 mapping of mouse kidney at a temporal resolution of ~3 min. The validity of this method was first demonstrated in vitro on a phantom with different concentrations of MnCl2 by comparing to the conventional spin echo T1 mapping method and a previously validated saturation recovery Look-Locker (SRLL) method and then in vivo on mouse kidneys at both pre- and post-MnCl2 infusion by comparing to SRLL.

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