Saturation Recovery Fast Spin Echo Method for Rapid T1 Mapping of Mouse Kidney
Kai Jiang1, Hui Tang1, Prassana K. Mishra2, Slobodan I. Macura2, and Lilach O. Lerman1
1Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, United States, 2Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, United States
In this study, a saturation recovery
fast spin echo method was developed for fast T1 mapping of mouse
kidney at a temporal resolution of ~3 min. The validity of this method was
first demonstrated in vitro on a
phantom with different concentrations of MnCl2 by comparing to the
conventional spin echo T1 mapping method and a previously validated
saturation recovery Look-Locker (SRLL) method and then in vivo on mouse kidneys at both pre- and post-MnCl2
infusion by comparing to SRLL.
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