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Abstract #2879

Time Efficient ASL Imaging with Segmented Multiband-acquisition (TEAISM)

Xiufeng Li1, Dingxin Wang1,2, Edward J. Auerbach1, Steen Moeller1, Gregory J. Metzger1, and Kamil Ugurbil1

1Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States, 2Siemens Medical Solutions USA Inc., Minneapolis, MN, United States

Recent studies have demonstrated the benefits of multi-band (MB) EPI for high-resolution whole brain PCASL imaging. However, the intrinsic nature of spatially interleaved simultaneous slice acquisition of MB-EPI requires a post-labeling delay larger than the longest arterial transit time in the brain, resulting in SNR efficiencies in the inferior or middle-inferior slices only comparable to or lower than those in SB-EPI PCASL imaging. To overcome the limitations of traditional MB-EPI and further improve SNR efficiencies of whole-brain high-resolution PCASL imaging, an alternative imaging acquisition strategy has been proposed and demonstrated: Time Efficient ASL Imaging with Segmented Multiband-acquisition (TEAISM).

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