Xiufeng Li1, Dingxin Wang1,2, Edward J. Auerbach1, Steen Moeller1, Gregory J. Metzger1, and Kamil Ugurbil1
1Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States, 2Siemens Medical Solutions USA Inc., Minneapolis, MN, United States
Recent studies have demonstrated the benefits of
multi-band (MB) EPI for high-resolution whole brain PCASL imaging. However, the
intrinsic nature of spatially interleaved simultaneous slice acquisition of
MB-EPI requires a post-labeling delay larger than the longest arterial transit time in the
brain, resulting in SNR efficiencies in the inferior or middle-inferior slices only
comparable to or lower than those in SB-EPI PCASL imaging. To overcome the limitations
of traditional MB-EPI and further improve SNR efficiencies of whole-brain
high-resolution PCASL imaging, an alternative imaging acquisition strategy has
been proposed and demonstrated: Time Efficient ASL Imaging
with Segmented Multiband-acquisition (TEAISM).
