Abstract #2879

Time Efficient ASL Imaging with Segmented Multiband-acquisition (TEAISM)

Xiufeng Li¹, Dingxin Wang^1,2, Edward J. Auerbach¹, Steen Moeller¹, Gregory J. Metzger¹, and Kamil Ugurbil¹

¹Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States, ²Siemens Medical Solutions USA Inc., Minneapolis, MN, United States

Recent studies have demonstrated the benefits of multi-band (MB) EPI for high-resolution whole brain PCASL imaging. However, the intrinsic nature of spatially interleaved simultaneous slice acquisition of MB-EPI requires a post-labeling delay larger than the longest arterial transit time in the brain, resulting in SNR efficiencies in the inferior or middle-inferior slices only comparable to or lower than those in SB-EPI PCASL imaging. To overcome the limitations of traditional MB-EPI and further improve SNR efficiencies of whole-brain high-resolution PCASL imaging, an alternative imaging acquisition strategy has been proposed and demonstrated: Time Efficient ASL Imaging with Segmented Multiband-acquisition (TEAISM).

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