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Abstract #2921

Respiratory self-gating in 3D UTE lung acquisition in small animal imaging

Marta Tibiletti1, Andrea Bianchi2, Åsmund Kjørstad3, Detlef Stiller2, and Volker Rasche1,4

1Core Facility Small Animal MRI, Ulm University, Ulm, Germany, 2Target Discovery Research, In-vivo imaging laboratory, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Germany, 3Department of Neuroradiology, University Hospital Hamburg-Eppendorf, Hamburg, Germany, 4Department of Internal Medicine II, Ulm University, Ulm, Germany

1D (k-space center) and 3D (sliding window 3D reconstruction) have been evaluated for respiratory retrospective self-gating for Quasi Random UTE-3D lung acquisition in freely breathing rats. Low-resolution 3D GRASP reconstruction allowed the extraction of an effective gating signal from changes in lung-liver interface position. The 1D center-of-k-space method did not yield sufficient gating signal fidelity, most likely caused by the only limited changes of the anatomy in the investigated volume, and to a lesser extent intensity modulations introduced by residual eddy-currents.

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