Abstract #2921

Respiratory self-gating in 3D UTE lung acquisition in small animal imaging

Marta Tibiletti¹, Andrea Bianchi², Åsmund Kjørstad³, Detlef Stiller², and Volker Rasche^1,4

¹Core Facility Small Animal MRI, Ulm University, Ulm, Germany, ²Target Discovery Research, In-vivo imaging laboratory, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Germany, ³Department of Neuroradiology, University Hospital Hamburg-Eppendorf, Hamburg, Germany, ⁴Department of Internal Medicine II, Ulm University, Ulm, Germany

1D (k-space center) and 3D (sliding window 3D reconstruction) have been evaluated for respiratory retrospective self-gating for Quasi Random UTE-3D lung acquisition in freely breathing rats. Low-resolution 3D GRASP reconstruction allowed the extraction of an effective gating signal from changes in lung-liver interface position. The 1D center-of-k-space method did not yield sufficient gating signal fidelity, most likely caused by the only limited changes of the anatomy in the investigated volume, and to a lesser extent intensity modulations introduced by residual eddy-currents.

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