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Abstract #3017

Diffusion Kurtosis Breast Imaging model – Which should be the highest b-value?

Filipa Borlinhas1, Luísa Nogueira2, Sofia Brandão3, Rita G. Nunes1, Raquel Conceição1,4, Joana Loureiro3, Isabel Ramos3, and Hugo A. Ferreira1

1Instituto de Biofísica e Engenharia Biomédica, Faculdade de Ciências da Universidade de Lisboa, Lisboa, Portugal, 2Escola Superior de Tecnologia da Saúde fo Porto, ESTSP/IPP, Porto, Portugal, 3Hospital de São João, Porto, Porto, Portugal, 4Institute of Biomedical Engineering, University of Oxford, United Kingdom, Oxford, United Kingdom

For the application of the Diffusion Kurtosis Imaging (DKI) model, the use of higher b values is advised. Here, the diagnostic performance of the DKI model in the differentiation of benign and malignant breast tumors was studied for the first time regarding the most suitable higher b-value (2000, and 3000 s/mm2). In this study were included 36 benign and 75 malignant lesions, assessed using combinations of b-values 50 to 2000, and to 3000s/mm2. The b-value range 50 to 3000 s/mm2 showed the best results regarding diagnostic performance and so this range is suggested for use in future DKI breast cancer studies.

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