Abstract #3292

Repeatability of Magnetic Resonance Fingerprinting on T1 and T2 quantification with the NIST/ISMRM standardized relaxation phantom

Yun Jiang¹, Dan Ma², Kathryn E. Keenan³, Karl Stupic³, Vikas Gulani^1,2, and Mark A. Griswold^1,2

¹Department of Biomedical Engineering, Case Western Reserve University, Clevleand, OH, United States, ²Department of Radiology, Case Western Reserve University, Clevleand, OH, United States, ³Physical Measurement Laboratory, National Institute of Standards and Technology, Boulder, CO, United States

In order to promote the clinical acceptance of quantitative relaxometry techniques as a valid biomarker, a fast quantitative method that can measure the relaxation parameters with high repeatability is needed. This study evaluates the repeatability of MRF with the standardized relaxometry phantom developed through collaboration between the ISMRM Ad Hoc Committee on Standards for Quantitative MR and the National Institute of Standards and Technology (NIST) over 35 consecutive days. A less than 5% variation on T₁ and T₂ estimations of MRF was observed in NIST standardized phantoms with a wide range of T1 and T2 values.

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