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Abstract #3351

Functional MRS at 7T and long TE

Petr Bednařík1,2,3, Ivan Tkáč1, Dinesh Deelchand1, Felipe Barreto1,4, Lynn E. Eberly5, Shalom Michaeli1, and Silvia Mangia1

1CMRR, Department of Radiology, University of Minnesota, Minneapolis, MN, United States, 2Central European Institute of Technology, Masaryk University, Brno, Czech Republic, 3Department of Medicine, University of Minnesota, Minneapolis, MN, United States, 4Department of Physics, University of Sao Paolo, Ribeirao Preto, Brazil, 5Division of Biostatistics, University of Minnesota, Minneapolis, MN, United States

With the goal of evaluating whether relaxation influences functional MRS (fMRS) results, we conducted fMRS experiments at 7T during visual stimulation using semi-LASER at 7T at long TE and short TR. The functional concentration changes of lactate (37%±6%) and glutamate (~5%±1%) observed here were consistent with previous results obtained at long TR and ultra-short TE. Small functional changes in signal intensity of NAA and Cr were also found, consistent with small changes in relaxations of those metabolites during visual stimulation.

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