Abstract #3351

Functional MRS at 7T and long TE

Petr Bednařík^1,2,3, Ivan Tkáč¹, Dinesh Deelchand¹, Felipe Barreto^1,4, Lynn E. Eberly⁵, Shalom Michaeli¹, and Silvia Mangia¹

¹CMRR, Department of Radiology, University of Minnesota, Minneapolis, MN, United States, ²Central European Institute of Technology, Masaryk University, Brno, Czech Republic, ³Department of Medicine, University of Minnesota, Minneapolis, MN, United States, ⁴Department of Physics, University of Sao Paolo, Ribeirao Preto, Brazil, ⁵Division of Biostatistics, University of Minnesota, Minneapolis, MN, United States

With the goal of evaluating whether relaxation influences functional MRS (fMRS) results, we conducted fMRS experiments at 7T during visual stimulation using semi-LASER at 7T at long TE and short TR. The functional concentration changes of lactate (37%±6%) and glutamate (~5%±1%) observed here were consistent with previous results obtained at long TR and ultra-short TE. Small functional changes in signal intensity of NAA and Cr were also found, consistent with small changes in relaxations of those metabolites during visual stimulation.

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