Abstract #3483

Combining Intravoxel Incoherent Motion Model and Reduced FOV for Evaluation of Single Renal Diffusion and Perfusion

CY Wang¹, R Zhang², L Jiang³, R Wang⁴, XD Zhang⁴, H Wang³, K Zhao⁴, LX Jin³, J Zhang^1,2, XY Wang^1,4, and J Fang^1,2

¹Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China, People's Republic of, ²College of Engineering, Peking University, Beijing, China, People's Republic of, ³Philips Healthcare, Suzhou, China, People's Republic of, ⁴Department of Radiology, Peking University First Hospital, Beijing, China, People's Republic of

The sequence most commonly used in renal DWI is based on single-shot echo-planar imaging (SS-EPI), which is prone to artifacts and distortions related to susceptibility and eddy currents. Reducing these artifacts and distortions in SS-EPI generally requires a reduced field of view (rFOV) in the phase-encoding direction and/or reduced spatial resolution. To resolve these problems, a 2D rFOV-DWI sequence was introduced for imaging and further IVIM modeling. Compared with conventional full-FOV single-shot DWI techniques, rFOV-DWI methods generally produced images of superior quality. With the application of IVIM model, it is possible to evaluate single renal diffusion and perfusion simultaneously.

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