Abstract #3484

Super-Resolution Track Density Imaging of 1.4 mm isotropic 7T Whole-Brain Diffusion Magnetic Resonance Images

Ralf Lützkendorf¹, Robin M. Heidemann², Thorsten Feiweier², Michael Luchtmann³, Sebastian Baecke¹, Joern Kaufmann⁴, Joerg Stadler⁵, Eike Budinger⁵, and Johannes Bernarding¹

¹Biometry and Medical Informatics, University of Magdeburg, Magdeburg, Germany, ²Siemens Healthcare GmbH, Erlangen, Germany, ³Department of Neurosurgery, University of Magdeburg, Magdeburg, Germany, ⁴Department of Neurology, University of Magdeburg, Magdeburg, Germany, ⁵Leibniz Institute for Neurobiology, Magdeburg, Germany

Track-density imaging (TDI) is a method to generate super-resolution images from fiber-tracking data (1). Here, we applied this technique to 1.4 mm isotropic 7T whole brain diffusion MR imaging data (dMRI). Besides the well-known large and medium-sized fiber tracts the high resolution of the data allowed visualizing the complex interwoven courses of fiber tracts in the cerebellar-pontine angle as well as showing parts of the trigeminus nerve. Combining TDI with high-resolved diffusion data has a great potential for analyzing the anatomy in vivo of brain structures across different scales as well as the neuronal connectome throughout the whole brain.

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