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Abstract #3489

Comparison of IVIM and BOLD MR imaging in Functional Evaluation of Diabetic nephropathy

Lihua Chen1, Tao Ren1, Yu Zhang2, Chenglong Wen1, and Wen Shen1

1Tianjin First Center Hospital, Tianjin, China, People's Republic of, 2Philips healthcare, Beijing, China, People's Republic of

To detect the changes of kidney diseases, magnetic resonance imaging(MRI) as a noninvasive approach has been proved to be more suitable for detecting and monitoring diabetic nephropathy(DN). Intravoxel incoherent motion (IVIM) and blood oxygenation level dependent (BOLD) MR imaging have been confirmed their high potential in detecting changes of renal function in patients with chronic renal diseases and transplanted kidneys. We compared the parameters of IVIM and BOLD in patients with DN and heathy controls. The results demonstrated the capacity of IVIM and BOLD for reflecting renal perfusion, diffusion and oxygenation changes in patients with DN.

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