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Abstract #3608

The effect of sonication duration on ablation depth during MR-guided focused ultrasound of bone: acute findings with MR in a swine model

Matthew Bucknor1, Rutwik Shah1, Eugene Ozhinsky1, and Viola Rieke1

1Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States

One challenge in magnetic resonance guided focused ultrasound ablation of bone lesions is extending the ablation zone deep to the cortical surface in order to cover the full intramedullary extent of the lesion. Extension of the ablation zone is important for complete treatment of for example, osteoid osteomas, and improved local control of metastatic bone disease. This study used a swine model to compare differences in the depth of the ablation zone between two protocols using short versus longer sonications, respectively, while maintaining the same overall sonication energy (by adjusting acoustic power).

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